Oestrogel 60 mg is gel for a cutaneous application containing 60 mg of Estradiol used in estrogen hormone replacement therapy (HRT) to substitute for the lack of oestrogen production. It is used to relieve symptoms of menopause caused by oestrogen deficiency. Oestrogel also stimulates the development of female sexual characteristics and is used as the oestrogen component of transgender hormone therapy for male-to-female transsexuals.